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GLP-1 isn't just an incretin - it's a full gut–brain–pancreas signaling axis. ➡️ Boosts satiety ➡️ Enhances insulin release ➡️ Slows gastric emptying Net effect: better glucose control + reduced food intake.
When cortisol levels remain elevated chronically—due to ongoing stress, poor sleep, or metabolic dysfunction—the body may store more fat, particularly around the abdomen, and resist weight loss efforts
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Exposure-response analysis for evaluation of semaglutide dose levels in type 2 diabetes